At the Garin-Shkolnik Laboratory, we investigate the molecular mechanisms underlying neurological and dermatological diseases, translating scientific discoveries into innovative therapeutic strategies. Led by Dr. Tali Garin-Shkolnik, MD, PhD, at Rambam Health Care Campus, our research combines molecular genetics, advanced gene-editing technologies, cellular biology, and clinical insight to address important unmet medical needs. From understanding disease mechanisms to developing tomorrow's targeted therapies.
The Garin-Shkolnik Laboratory is a translational research group developing innovative therapies for severe neurological and dermatological diseases. We combine molecular research, advanced genome-editing technologies, disease models and clinical insight to translate scientific discoveries into meaningful therapeutic strategies.
We develop precision genetic therapies for severe neurogenetic disorders, with a major focus on GRIN2B-related neurodevelopmental disorders.
Our work emphasizes next-generation genome-editing technologies capable of correcting disease-causing variants directly at the DNA level.
We investigate molecular and cellular mechanisms underlying chronic inflammatory and neoplastic skin diseases and use these discoveries to develop new therapeutic strategies.
Primary research areas:
Developing genetic therapies for GRIN2B-related neurodevelopmental disorders.
Learn more →Applying next-generation genome-editing technologies to precisely correct disease-causing genetic variants.
Learn more →Investigating mechanisms responsible for persistent inflammation, disease recurrence and therapeutic response.
Learn more →Exploring malignant T-cell biology and new therapeutic strategies for mycosis fungoides and CTCL.
Learn more →Clinical observations guide the questions we investigate. We combine molecular biology, cellular systems, disease models and advanced therapeutic technologies to move promising discoveries toward clinical translation.
Explore recent publications from the Garin-Shkolnik Laboratory and our collaborating research groups.
View PublicationsOur multidisciplinary team brings together expertise in dermatology, molecular biology, genome editing, neurobiology, disease modelling and translational medicine.
Meet the TeamRecent publications and scientific discoveries from the lab.
Read more →New developments across our gene-editing and dermatology programs.
Read more →We welcome highly motivated students and researchers interested in translational biomedical research and the development of new therapies.
Department of Dermatology
Rambam Health Care Campus
Haifa, Israel